Email charityadmin@mlsrf.co.uk Charity number:1139383 President: Sir Paul Nurse

Cancer Research

ATAC on tumour time: Defining the time-of-day variation in the cistrome of solid tumours

The biological clock, a.k.a. the circadian timing system, modulates behavior and physiology and synchronises human beings to the environmental cycles of night and day. For example, blood pressure rises along with heart rate even before we wake up to prepare us for getting out of bed.

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MLS funding to better understand small cell lung cancer and improve treatment regimes.

Small cell lung cancer is an aggressive form of lung cancer notorious for its rapid progression and poor outcome. The average survival time from diagnosis is only 9 months.

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Comparing urinary volatile organic compound (VOC) biomarkers with faecal occult blood testing as a screening tool for colorectal cancer

We will evaluate a new, more sensitive and acceptable method to detect bowel cancer – using a urine test. Bowel cancer is common and many people have advanced disease at diagnosis. Bowel cancer screening involves people with

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3-dimensional imaging of cancer cells by electron tomography

A number of metal-based compounds with promising anti-proliferative activity toward a wide range of tumours with novel mechanisms of action have recently been discovered. Such new ...

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Brain Cancer

We work on Glioblastoma Multiforme (GBM), the most deadly variety of brain cancer. Tumours of any type require a blood supply, which is usually created by branching from normal blo...

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Characterisation of Volatile Organic Compounds (VOCs) in the urine and stools of colorectal cancer (CRC) patients, their first degree relatives and co-habitors

Project summary: To determine to what extent colorectal cancer is due to genetic predisposition and environmental factors (nature vs nurture). This will be done by analysing the p...

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Pilot study to develop methodologies and acquire data, allowing elucidation of the coordinated control of splicing in oestrogen positive and negative breast cancer tissues.

Although breast cancer treatment has improved over the past few decades and led to increased survival rates and better quality of life, over 44,000 women in the UK are diagnosed wi...

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Multifunctional nanocomposites as dual cancer diagnostic and therapeutic tools

My work aims to develop unique materials which are capable of functioning as all-in-one medical diagnostic and therapeutic devices – the emerging field of ‘theranostics

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Supporting carefully selected research projects in Warwickshire universities, hospitals and Wellesbourne Crop Centre