Email charityadmin@mlsrf.co.uk Charity number:1139383 President: Sir Paul Nurse

Infection Research

Developing new diagnostics for bone and joint infections

Prosthetic joint infections have a huge impacts on patients’ quality of life and healthcare systems worldwide. The goal of this Medical and life sciences Research funded project is to aid accurate diagnostics for S. aureus bone and joint infections.

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A predictive model for COVID-19

Supported by the Medical and Life Sciences Research Fund, Research Scientist Emma Braybrook at University Hospital Coventry and Warwickshire will use data from Covid-19 patients to monitor, characterise and ultimately predict Covid-19 pathology and devise intervention strategies. The proposal uses extensive expertise and facilities at the hospital and Warwick University to improve disease understanding and management.

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A novel system to use bacteriophages as tools to detect bacteria

The Medical and Life Sciences Research Fund is supporting this collaboration between Warwick University Schools of Engineering and Life Sciences to use bacteriophages as tools to detect bacteria. This novel and potentially effective system could help developing countries and those who lack access to advanced biomedical testing facilities with a cheap and rapid device for the diagnosis and treatment of bacterial infections.

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Gut infection

The Medical and Life Sciences Research Fund grant awarded to Mr Jeffrey Cheng at Warwick School of Life Sciences will be used to research cutting edge sequencing methodologies along with human gut mimics to investigate Clostridioides difficile infections and identify bacterial proteins which are important for establishment of infection.

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Tackling bacterial transmission

A bacterial pathogen called Campylobacter jejuni is the most common cause of bacterial gastroenteritis in developed countries and is thought to be transmitted from chickens to humans.

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Antibiotic therapy and UTIs

Urinary tract infections (UTIs) are one of the most common infections encountered in individuals of all ages. They affect over 4 million people in the UK every year, and account for 1-3% of GP consultations.

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New antibacterial approaches

Antibiotics have been the backbone of medical advances and treatment for decades but this ability to kill harmful bacteria is threatened, both now and in the future, by the development of resistance in those bacteria to these lifesaving drugs.

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Discovery of antimicrobials active against Clostridium difficile from actinomycete gene clusters

Antimicrobial resistance (AMR) is recognised as one of the major threats to human health, and is currently believed to be the cause for at least 50,000 deaths each year across Europe and the US alone. Due to AMR, it is estimated that global consumption of antibiotics in human medicine has increased by 40% between 2000 and 2010.

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Antibiotics Research

The Medical and Life Sciences Research Fund was delighted to receive a very special grant from a local charity to support antibiotics research.  Without new antibiotics things we a...

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Overcoming resilient bacterial infection

Recurrent bacterial infections that are resilient to treatment are a huge clinical challenge. Lucy Frost works with scientists and clinicians at Warwick Medical School to understand how bacteria invade and survive our host defence systems.

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Supporting carefully selected research projects in Warwickshire universities, hospitals and Wellesbourne Crop Centre