Cellular control via circadian clock

Each of our cells contains a biological timer, a so-called circadian clock, that is used to coordinate a vast array of cellular processes and allocate resources throughout the day. In most cells, this clock controls the rate of division, as well as the time-of-day differences in the way the cell interacts with drugs. In cancer cells, however, this clock can be broken.

Dr James Jarrold has been awarded Medical and Life Sciences Research funding to generate control data from healthy breast tissue using next generation sequencing  (NGS) in order to build a better model of the clock in breast tissue; with the goal of learning more about how the circadian clock is linked to survival and other aspects of breast cancer.