Email charityadmin@mlsrf.co.uk Charity number:1139383 President: Sir Paul Nurse

Modelling infection susceptibility to Covid19

Miss Agnieszka Nagorska
Warwick Medical School

The symptoms of the SARS-CoV2 infection are extremely variable, ranging from some individuals being completely asymptomatic to others having severe respiratory and organ failure. It is not known why some individuals have higher prevalence to infection with Covid19. A number of research groups have recently identified a role for the protein FURIN as an activating factor of the Covid19 infection.

In this project Agnieszka Nagorska, a PhD student at Warwick Medical School aims to explore the link between Furin’s role in cardiac development, using zebrafish as a model and the potential infection susceptibility to Covid19.

This research which the Medical and Life Sciences Research Fund is providing funding has a potential to address many interesting questions regarding heart development though uncovering of the novel mechanisms of molecular factors and whether these affect susceptibility to infection with Covid-19.

Supporting carefully selected research projects in Warwickshire universities, hospitals and Wellesbourne Crop Centre